Is there an interference between maternal immunity MDA and vaccination on the first day of the chicks’ life, and can we vaccinate IB at the age of 7 days?
Dr. Milad Ibrahim Urabi
Regarding the first question:
Vaccination by eye drops or spray on the first day of the bird’s life stimulates rapid lasting protection, and this protection depends on stimulating the harderian gland and depends on the production of antibodies produced and released from the eye (tears).
Where these secretions flowing into the oral cavity through the eye and nasal canal can help to provide complete protection inside the pharyngeal system, so the Gumboro disease and Newcastle disease do not interfere with the antibodies of the mothers with the vaccine given on the first day, and this is the world source (Davelaar and Kouwenhoven).
Regarding the second question:
It is known that maternal immunoglobulin (MDA) provides complete protection for the deep organs, especially the genital organs, especially females in mothers and laying hens, so that a false layer does not occur and thus the loss of the flock. Therefore, from a scientific point of view, as happens in Newcastle disease (ND), the spray vaccine and the drop vaccine are the best solution for vaccination to stimulate local immunity.
Therefore, vaccination can be done at the age of one day for the bird and there is no conflict with maternal immunity (MDA). Scientists have noticed that vaccination for bronchitis (IB) at the age of (5-10) days provides less effective protection than vaccination at the age of one day.
Scientists gave the (IB) vaccine as eye drops at 8 days of age and after the challenge at 30 days of age this group was less protected than the rest of the groups vaccinated at 1 day, 15 days of age and 20 days of age. There is a very important point that the chicks vaccinated with (IB) at 8 days of age will suffer from conjunctivitis and clear respiratory signs, especially in the trachea. The reason is that during this period the sensitivity of the Harderian gland to the infectious bronchitis virus increases. Another important reason is that this gland is not physiologically prepared to be stimulated or activated to form local immunity. Therefore, it is necessary, even obligatory, to vaccinate on the first day of the bird’s life.
