{"id":4735,"date":"2025-07-14T15:27:11","date_gmt":"2025-07-14T12:27:11","guid":{"rendered":"https:\/\/nahrainveterinary.com\/?p=4735"},"modified":"2025-07-14T15:27:11","modified_gmt":"2025-07-14T12:27:11","slug":"how-antibodies-are-made-and-how-they-destroy-antibodies","status":"publish","type":"post","link":"https:\/\/nahrainveterinary.com\/ar\/how-antibodies-are-made-and-how-they-destroy-antibodies\/","title":{"rendered":"\u0643\u064a\u0641\u06cc\u0629 \u0635\u0646\u0627\u0639\u0629 \u0627\u0644\u0627\u062c\u0633\u0627\u0645 \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u0648\u0643\u064a\u0641\u06cc\u0629 \u064a\u0642\u0636\u064a \u0639\u0644\u0649 \u0627\u0644\u062c\u0633\u0645 \u0627\u0644\u0645\u062a\u0636\u062f"},"content":{"rendered":"

\u0643\u064a\u0641\u06cc\u0629 \u0635\u0646\u0627\u0639\u0629 \u0627\u0644\u0627\u062c\u0633\u0627\u0645 \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u0648\u0643\u064a\u0641\u06cc\u0629 \u064a\u0642\u0636\u064a \u0639\u0644\u0649 \u0627\u0644\u062c\u0633\u0645 \u0627\u0644\u0645\u062a\u0636\u062f<\/p>\n

\"\"<\/p>\n

Dr. Mila Ibrahim Urabi<\/p>\n

14 \/ 7\/ 2025<\/p>\n

\u0627\u0644\u0643\u062b\u064a\u0631 \u0645\u0646 \u0627\u0647\u0644 \u0627\u0644\u0627\u062e\u062a\u0635\u0627\u0635 \u064a\u0639\u0631\u0641\u0648\u0646 \u0627\u0646 \u0644\u0643\u0644 \u0645\u0633\u062a\u0636\u062f Antigens \u062a\u0648\u062c\u062f \u0627\u062c\u0633\u0627\u0645 \u0645\u0646\u0627\u0639\u064a\u0647 \u0644\u0647 \u060c \u0648\u0627\u0644\u064a\u0648\u0645 \u0633\u0648\u0641 \u0627\u0642\u0648\u0645 \u0628\u0634\u0631\u062d \u0627\u0644\u0627\u0644\u064a\u0647 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0647 \u0644\u0647\u0630\u0647 \u0627\u0644\u0639\u0645\u0644\u064a\u0647 .<\/p>\n

 <\/p>\n

\u0645\u0627 \u0647\u0648 \u0627\u0644\u062c\u0633\u0645 \u0627\u0644\u0645\u0633\u062a\u0636\u062f<\/p>\n

\u064a\u0643\u0648\u0646 \u0634\u0643\u0644 \u0627\u0644\u062c\u0633\u0645 \u0627\u0644\u0645\u062a\u0636\u062f ( Antibodies ) \u0639\u0644\u0649 \u0634\u0643\u0644 \u062d\u0631\u0641 ( Y ) \u0648 \u064a\u062a\u0643\u0648\u0646 \u0645\u0646 \u0633\u0644\u0633\u0644\u062a\u064a\u0646\u060c \u0627\u0644\u0633\u0644\u0633\u0644\u0647 \u0627\u0644\u062b\u0642\u064a\u0644\u0647 ( heavy ) \u0648 \u0627\u0644\u0633\u0644\u0633\u0644\u0647 \u0627\u0644\u062e\u0641\u064a\u0641\u0629 ( light ) \u0648 \u0627\u0644\u062a\u064a \u0647\u064a \u0639\u0628\u0627\u0631\u0647 \u0639\u0646 \u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0645\u0643\u0648\u0646\u0629 \u0645\u0646 \u0645\u0646\u0637\u0642\u062a\u064a\u0646 \u0647\u0645\u0627 \u0627\u0644\u0627\u0648\u0644\u0649 ( variable antibody region ) \u0648 \u0627\u0644\u062a\u064a \u062a\u062a\u0638\u0645\u0646 \u0641\u064a \u0646\u0647\u0627\u064a\u062a\u0647\u0627 \u0627\u0644\u0633\u0644\u0633\u0644\u0629 \u0627\u0644\u062e\u0641\u06cc\u0641\u0629 \u0648 \u0627\u0644\u062b\u0642\u06cc\u0644\u0629 (the light and heavy chains ). \u0627\u0644\u0645\u0646\u0637\u0642\u0629 \u0627\u0644\u062b\u0627\u0646\u064a\u0629 \u0647\u064a \u0627\u0644\u0645\u0646\u0637\u0642\u0629 \u0627\u0644\u062b\u0627\u0628\u062a\u0629 ( constant region ) \u0648\u0627\u0644\u062a\u064a \u062a\u0642\u0648\u0645 \u0628\u062a\u062d\u062f\u06cc\u062f \u0639\u0645\u0644\u06cc\u0629 \u062a\u062f\u0645\u06cc\u0631 \u0648 \u0627\u0644\u062a\u062e\u0644\u0635 \u0645\u0646 \u0627\u0644\u0645\u0633\u062a\u0636\u062f ( determines the mechanism used to destroy antigen ).<\/p>\n

\u062a\u062d\u062a\u0648\u064a \u0645\u0646\u0637\u0642\u0629 \u0627\u0644\u0633\u0644\u0633\u0644\u0629 \u0627\u0644\u062e\u0641\u06cc\u0641\u0629 ( light chain ) \u0639\u0644\u0649 (\u0662\u0662\u0660) \u062d\u0645\u0636 \u0623\u0645\u06cc\u0646\u064a \u060c \u0623\u0645\u0627 \u0645\u0646\u0637\u0642\u0629 \u0627\u0644\u0633\u0644\u0633\u0644\u0629 \u0627\u0644\u062b\u0642\u06cc\u0644\u0629 ( heavy chain) \u0641\u062a\u062d\u062a\u0648\u064a \u0639\u0644\u0649 (\u0664\u0664\u0660) \u062d\u0645\u0636 \u0627\u0645\u06cc\u0646\u064a . \u062a\u0648\u062c\u062f \u0645\u0646\u0637\u0642\u0647 \u062a\u0633\u0645\u0649 hypervariable region (HVR) \u0647\u064a \u0627\u0644\u062a\u064a \u0633\u0648\u0641 \u062a\u0642\u0648\u0645 \u0628\u0645\u0633\u0643 \u0627\u0644\u0633\u0644\u0633\u0644\u0629 \u0627\u0644\u062b\u0642\u06cc\u0644\u0629 \u0645\u0639 \u0627\u0644\u0633\u0644\u0633\u0644\u0629 \u0627\u0644\u062e\u0641\u06cc\u0641\u0629. \u0627\u0644\u0633\u0644\u0633\u0644\u0629 \u0627\u0644\u062b\u0642\u06cc\u0644\u0629 \u0648 \u062a\u062a\u0643\u0648\u0646 \u0645\u0646 \u0623\u0631\u0628\u0639\u0629 \u0645\u0646\u0627\u0637\u0642( \u0627\u0644\u0645\u0646\u0637\u0642\u0647 \u0627\u0644\u0645\u062a\u063a\u0627\u064a\u0631\u0629 \u0648\u062b\u0644\u0627\u062b \u0645\u0646\u0627\u0637\u0642 \u062b\u0627\u0628\u062a\u0629). \u0628\u064a\u0646\u0645\u0627 \u062a\u062a\u0643\u0648\u0646 \u0627\u0644\u0633\u0644\u0633\u0644\u0647 \u0627\u0644\u062e\u0641\u064a\u0641\u0647 \u0645\u0646 \u0645\u0646\u0637\u0642\u0647 \u0648\u0627\u062d\u062f\u0647 \u0645\u062a\u063a\u0627\u064a\u0631\u0647 \u0648\u0645\u0646\u0637\u0642\u0647 \u062b\u0627\u0628\u062a\u0647 \u0648\u0627\u062d\u062f\u0647 . \u0627\u0644\u062a\u0642\u0627\u0621 \u0627\u0644\u0645\u0646\u0637\u0642\u062a\u064a\u0646 \u064a\u0633\u0645\u0649 \u0645\u0646\u0637\u0642\u0647 \u0627\u0644\u0645\u0641\u0635\u0644.\n\u062a\u0648\u062c\u062f \u0645\u0646\u0637\u0642\u0647 \u0641\u064a \u0646\u0647\u0627\u064a\u0647 \u062a\u0642\u0648\u064a\u0633 \u0627\u0644 V \u062a\u0633\u0645\u0649 \u0645\u0646\u0637\u0642\u0647 \u0627\u0644\u0645\u0641\u0635\u0644 \u0648\u0647\u0630\u0647 \u0627\u0644\u0645\u0646\u0637\u0642\u0647 \u062a\u0643\u0648\u0646 \u063a\u0646\u064a\u0629 \u0628\u0631\u0648\u0627\u0628\u0637 \u0623\u0648 \u0623\u0648\u0627\u0635\u0631 \u0643\u0628\u0631\u064a\u062a\u064a\u0629 \u062b\u0646\u0627\u0626\u064a\u0629 \u062a\u0633\u062a\u0637\u064a\u0639 \u0623\u0646 \u062a\u062c\u0639\u0644 \u0647\u0630\u0627 \u0627\u0644\u0645\u0641\u0635\u0644 \u064a\u0641\u062a\u062d \u0627\u0644\u0630\u0631\u0627\u0639\u064a\u0646 (\u0661\u0668\u0660 ) \u062f\u0631\u062c\u0629 \u0648 \u064a\u0635\u0628\u062d \u0627\u0644\u062c\u0633\u0645 \u0627\u0644\u0645\u0636\u0627\u062f \u0639\u0644\u0649 \u0634\u0643\u0644 \u062d\u0631\u0641 (T ) \u060c \u0623\u064a \u062a\u0639\u0637\u064a \u0645\u0631\u0648\u0646\u0629 \u0641\u064a \u062d\u0631\u0643\u0629 \u0627\u0644\u0645\u0641\u0635\u0644\u060c \u0648 \u0627\u0644\u062a\u064a \u0633\u0648\u0641 \u062a\u0639\u0637\u064a \u0645\u0633\u0627\u062d\u0629 \u0623\u0643\u0628\u0631 \u0644\u0648\u0635\u0644 \u0644\u0644\u0627\u0646\u062a\u062c\u064a\u0646. \u062a\u0648\u062c\u062f \u0645\u0646\u0637\u0642\u0647 \u0645\u0647\u0645\u0629 \u062c\u062f\u0627 \u062a\u0633\u0645\u0649 \u0627\u0644\u0645\u0646\u0637\u0642\u0629 \u0634\u062f\u064a\u062f\u0629 \u0627\u0644\u062a\u063a\u0627\u064a\u0631 \u0648 \u0627\u0644\u062a\u064a \u0630\u0643\u0631\u062a \u0623\u0639\u0644\u0627\u0647 ( HVR) \u0648 \u0647\u0630\u0647 \u0627\u0644\u0645\u0646\u0637\u0642\u0629 \u0647\u064a \u0627\u0644\u0627\u0633\u0627\u0633 \u0641\u064a \u062a\u063a\u0627\u064a\u0631 \u0627\u0644\u062c\u0633\u0645 \u0627\u0644\u0645\u0636\u0627\u062f \u0625\u0639\u062a\u0645\u0627\u062f\u0627 \u0639\u0644\u0649 \u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0627\u0644\u0627\u0646\u062a\u062c\u064a\u0646 \u0648 \u0628\u0627\u0644\u062a\u0627\u0644\u064a \u0647\u0630\u0647 \u0627\u0644\u0645\u0646\u0637\u0642\u0629 \u0647\u064a \u0627\u0644\u062a\u064a \u0633\u0648\u0641 \u062a\u062d\u062f\u062f \u062e\u0635\u0648\u0635\u064a\u0629 \u0627\u0644\u062c\u0633\u0645 \u0627\u0644\u0645\u0636\u0627\u062f \u0627\u0644\u0645\u062e\u0635\u0635 \u0644\u0644\u0645\u0633\u062a\u0636\u062f.<\/p>\n

\u064a\u0648\u062c\u062f \u0646\u0648\u0639\u0627\u0646 \u0645\u0646 \u0627\u0644\u062c\u0633\u0645 \u0627\u0644\u0645\u0636\u0627\u062f ( IgA) \u062a\u0643\u0648\u0646\u0647\u0645\u0627 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0628\u0644\u0627\u0632\u0645\u0627 ( plasma cell ) \u0647\u0645\u0627 :<\/p>\n

    \n
  1. \u0627\u0644\u062c\u0633\u0645 \u0627\u0644\u0645\u0636\u0627\u062f \u0627\u0644\u0625\u0641\u0631\u0627\u0632\u064a (Secretory antibodies ) \u0648\u0647\u0648 \u0627\u0644\u0645\u0633\u0624\u0648\u0644 \u0639\u0646 \u0627\u0644\u062a\u0648\u0633\u0637 \u0641\u064a \u0625\u0632\u0627\u0644\u0629 \u0627\u0644\u0645\u0633\u062a\u0636\u062f\u0627\u062a \u0645\u0646 \u0627\u0644\u0635\u0641\u064a\u062d\u0629 \u0627\u0644\u0645\u062e\u0627\u0637\u064a\u0629 \u0627\u0644\u062e\u0627\u0635\u0629 ( mediate removal of antigens from the mucosal lamina propria ) \u0627\u0644\u0645\u0648\u062c\u0648\u062f \u0641\u064a \u0627\u0644\u062f\u0645.<\/li>\n
  2. \u0627\u0644\u0627\u062c\u0633\u0627\u0645 \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u0627\u0644\u0645\u0648\u0636\u0639\u06cc\u0629 ( locally Antibodies ) \u0648\u0647\u0648 \u0627\u0644\u0645\u0633\u0624\u0648\u0644 \u0639\u0646 \u0627\u0644\u0645\u0646\u0627\u0639\u0647 \u0627\u0644\u0645\u0648\u0636\u0639\u064a\u0647 \u0641\u064a \u0627\u0644\u0633\u0637\u0648\u062d \u0627\u0644\u0645\u0635\u0644\u064a\u0647.<\/li>\n<\/ol>\n

    \u0627\u0645\u0627 \u0628\u0627\u0642\u064a \u0627\u0644\u0627\u062c\u0633\u0627\u0645 \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u0641\u0647\u064a \u0641\u0642\u0637 \u0646\u0648\u0639 \u0648\u0627\u062d\u062f .<\/p>\n

     <\/p>\n

    \u0627\u0644\u0627\u0646 \u0644\u0648 \u0646\u062a\u0630\u0643\u0631 \u0627\u0644\u0645\u062d\u0627\u0636\u0631\u0629 \u0627\u0644\u0627\u0648\u0644\u0649 \u0648 \u0643\u064a\u0641 \u0623\u0646 \u062e\u0644\u0627\u064a\u0627 ( T CD4 cell ) \u0648 \u0645\u0627\u0630\u0627 \u0643\u0627\u0646\u062a \u062a\u0641\u0639\u0644 \u061f\u060c \u0648 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644 ( B cell ) \u0623\u064a\u0636\u0627 \u0633\u0648\u0641 \u062a\u0634\u0627\u0631\u0643 \u0641\u064a \u0639\u0645\u0644\u06cc\u0629 ( APC ) \u0643\u0645\u0627 \u062a\u0641\u0639\u0644 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644 ( T cell ) \u060c \u0648\u0628\u0627\u0644\u062a\u0627\u0644\u064a \u0633\u0648\u0641 \u062a\u0642\u0648\u0645 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644 ( B cell ) \u0628\u0639\u0631\u0636 \u0627\u0644\u0645\u0633\u062a\u0636\u062f \u0639\u0644\u0649 \u062c\u062f\u0627\u0631\u0647\u0627 \u0639\u0646 \u0637\u0631\u064a\u0642 \u0627\u0644 ( MHC ll ) \u0648 \u0633\u0648\u0641 \u062a\u0639\u0637\u064a \u0627\u0644\u0628\u064a\u0627\u0646\u0627\u062a \u0643\u0627\u0645\u0644\u0647 (\u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u0645\u0633\u062a\u0636\u062f \u0628\u0627\u0644\u062a\u0641\u0635\u064a\u0644 ) \u0627\u0644\u0649 \u062e\u0644\u0627\u064a\u0627 (T CD4 cell ) \u0648 \u0627\u0644\u062a\u064a \u0633\u0648\u0641 \u062a\u062a\u0645\u0627\u064a\u0632 \u0648 \u062a\u0646\u0634\u0637 \u0648 \u062a\u062a\u062d\u0648\u0644 \u0627\u0644\u0649 (Th2 ) \u0639\u0646 \u0637\u0631\u064a\u0642 \u0627\u0644\u0633\u0627\u064a\u062a\u0648\u0643\u064a\u0646\u0627\u062a \u0648 \u0627\u0644\u0627\u0646\u062a\u0631\u0644\u0648\u0643\u064a\u0646\u0627\u062a. \u0648\u0647\u0630\u0627 \u0627\u0644\u062a\u0641\u0627\u0639\u0644 \u0633\u0648\u0641 \u064a\u0641\u0631\u0632 \u0641\u064a\u0647 ( IL 4 ) \u0648 ( SATA 3 ) \u0648 \u0627\u0644\u0644\u0630\u0627\u0646 \u0633\u0648\u0641 \u064a\u0624\u062b\u0631\u0627\u0646 \u0639\u0644\u0649 \u062e\u0644\u064a\u0647 \u0627\u0644 ( B cell) \u0648 \u064a\u062c\u0639\u0644\u0647\u0627 \u062a\u062a\u0645\u064a\u0632 \u0648 \u062a\u062a\u062d\u0648\u0644 \u0627\u0644\u0649 \u062e\u0644\u0627\u06cc\u0627 \u0628\u0644\u0627\u0632\u0645\u06cc\u0629\u060c \u0623\u064a \u0628\u0645\u0639\u0646\u0649 \u0623\u0646 \u0627\u0644\u0627\u0646\u062a\u0631\u0644\u0648\u0643\u064a\u0646 \u0627\u0644\u0631\u0627\u0628\u0639 \u0639\u0646\u062f \u0625\u0641\u0631\u0627\u0632\u0647 \u0633\u0648\u0641 \u062a\u062a\u062d\u0648\u0644 \u062e\u0644\u064a\u0629 \u0627\u0644 ( B cell ) \u0627\u0644\u0649 \u062e\u0644\u064a\u0629 \u0628\u0644\u0627\u0632\u0645\u0627\u060c \u0648\u0637\u0631\u064a\u0642\u0647 \u0627\u0644\u062a\u062d\u0648\u0644 \u0633\u0648\u0641 \u0623\u0634\u0631\u062d\u0647\u0627 .\n\u0639\u0646\u062f \u0625\u0641\u0631\u0627\u0632 \u0627\u0644( IL4 ) \u0645\u0646 ( Th2 ) \u062a\u0648\u062c\u062f \u0645\u0633\u062a\u0642\u0628\u0644\u0627\u062a \u0639\u0644\u0649 \u0633\u0637\u062d \u062e\u0644\u0627\u06cc\u0627 (B cell ) \u0648 \u0647\u0630\u0647 \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644\u0627\u062a \u062a\u0631\u062a\u0628\u0637 \u0645\u0639 \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644\u0627\u062a ( ligand receptor ) \u0627\u0644\u0645\u0648\u062c\u0648\u062f \u0639\u0644\u0649 \u062e\u0644\u0627\u064a\u0627 (Th2 ) \u0648 \u0645\u0645\u0643\u0646 \u0623\u0646 \u064a\u0641\u0631\u0632 \u0627\u0644( IL4) \u0645\u0646 \u0623\u064a \u062e\u0644\u064a\u0629 \u0648 \u064a\u0624\u062b\u0631 \u0639\u0644\u0649 \u0646\u0641\u0633 \u0627\u0644\u062e\u0644\u064a\u0629 \u0627\u0644\u062a\u064a \u0623\u0641\u0631\u0632\u062a\u0647 \u0648 \u064a\u0633\u0645\u0649 ( auto Crain ) \u060c \u0648 \u06cc\u0645\u0643\u0646 \u0623\u0646 \u064a\u0624\u062b\u0631 \u0639\u0644\u0649 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u062c\u0627\u0648\u0631\u0629 \u0644\u0644\u062e\u0644\u064a\u0629 \u0627\u0644\u062a\u064a \u0641\u0631\u0632\u062a\u0629 \u0623\u0648 \u0645\u0645\u0643\u0646 \u0623\u0646 \u064a\u0624\u062b\u0631 \u0639\u0644\u0649 \u062e\u0644\u0627\u064a\u0627 \u0628\u0639\u064a\u062f\u0629 \u062c\u062f\u0627 \u0639\u0646 \u0637\u0631\u064a\u0642 \u0645\u062c\u0631\u0649 \u0627\u0644\u062f\u0645\u060c \u0628\u0639\u062f \u0630\u0644\u0643 \u0633\u0648\u0641 \u064a\u062d\u062f\u062b \u062a\u0645\u0627\u06cc\u06cc\u0632 \u0644\u062e\u0644\u0627\u06cc\u0627 ( B cell) \u0648 \u062a\u0639\u0628\u06cc\u0631 \u062c\u06cc\u0646\u064a( Gene expression).\n\u062a\u0648\u062c\u062f \u062a\u062d\u062a \u0645\u062d\u0641\u0638\u0647 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 (B cell ) \u0648 \u0641\u064a \u0627\u0644\u062c\u062f\u0627\u0631 \u0628\u0631\u0648\u062a\u06cc\u0646 ( jak protein ) \u0648 \u0647\u0630\u0627 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646 \u0645\u0648\u062c\u0648\u062f \u062a\u062d\u062a \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644\u0627\u062a \u0641\u064a \u0627\u0644\u062e\u0644\u064a\u0629 ( B ) \u0648 \u0633\u0648\u0641 \u064a\u062d\u062f\u062b \u0641\u064a\u0647 \u062a\u0641\u0639\u06cc\u0644 ( activation ) \u0644\u064a\u062d\u0641\u0632 \u0641\u064a \u062a\u0634\u063a\u064a\u0644 ( STAT signaling pathway ) \u060c \u0648\u0647\u0630\u0627 \u0628\u062f\u0648\u0631\u0647 \u0633\u0648\u0641 \u064a\u062d\u0641\u0632 ( gata 3 and fox D3 ) \u0627\u0644\u0645\u0648\u062c\u0648\u062f\u0629 \u0641\u064a \u0646\u0648\u0627\u0629 \u0627\u0644\u062e\u0644\u064a\u0629\u060c \u0648\u0647\u064a \u0639\u0648\u0627\u0645\u0644 ( Transcription factors ) \u0644\u062a\u062d\u0648\u064a\u0644 \u062e\u0644\u064a\u0629 \u0627\u0644 (B cell ) \u0627\u0644\u0649 \u062e\u0644\u064a\u0629 \u0628\u0644\u0627\u0632\u0645\u0627 .\u0647\u0630\u0647 \u0627\u0644\u062e\u0644\u064a\u0647 \u062a\u0643\u0648\u0646 \u0623\u0643\u062b\u0631 \u0628\u062f\u0627\u0646\u0629 \u0648 \u062a\u0642\u0631\u064a\u0628\u0627 \u0628\u064a\u0636\u0648\u064a\u0629 \u0627\u0644\u0634\u0643\u0644 \u0648 \u062a\u062d\u062a\u0648\u064a \u0639\u0644\u0649 \u0633\u0627\u064a\u062a\u0648\u0628\u0644\u0627\u0632\u0645 \u0643\u062b\u064a\u0641 \u0648 \u0643\u0628\u064a\u0631 \u0648 \u0641\u064a\u0647 \u0627\u0644\u0645\u0626\u0627\u062a \u0645\u0646 \u0627\u0644\u0631\u0627\u06cc\u0628\u0648\u0633\u0648\u0645\u0627\u062a . \u0627\u0644\u0627\u0646 \u062a\u062d\u0648\u0644\u062a \u062e\u0644\u064a\u0647 \u0627\u0644( B cell) \u0627\u0644\u0649 \u062e\u0644\u06cc\u0629 \u0628\u0644\u0627\u0632\u0645\u0627 \u060c \u0648\u0627\u0644\u0644\u0627\u0646 \u064a\u0623\u062a\u064a \u0627\u0644\u062f\u0648\u0631 \u0643\u064a\u0641\u06cc\u0629 \u0635\u0646\u0627\u0639\u0629 \u0627\u0644\u0627\u062c\u0633\u0627\u0645 \u0627\u0644\u0645\u0636\u0627\u062f\u0629 .<\/p>\n

    \u0627\u0644\u0627\u0646 \u0648\u0628\u0639\u062f \u0643\u0644 \u0647\u0630\u0627 \u0627\u0644\u0639\u0645\u0644\u064a\u0627\u062a \u0648\u0627\u0644\u062a\u0641\u0627\u0639\u0644\u0627\u062a \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0647 \u0627\u0635\u0628\u062d\u062a \u062e\u0644\u0627\u064a\u0627 Plasma cell \u0645\u0635\u0627\u0646\u0639 \u0645\u0639\u0627\u0645\u0644 \u0644\u0644\u0627\u062c\u0633\u0627\u0645 \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u0648 \u0633\u0648\u0641 \u0623\u0634\u0631\u062d \u0643\u064a\u0641 \u062a\u062a\u0645 \u0627\u0644\u0635\u0646\u0627\u0639\u0629 \u0641\u064a \u0647\u0630\u0647 \u0627\u0644\u0645\u0639\u0627\u0645\u0644 .\n\u062a\u0648\u062c\u062f \u062c\u064a\u0646\u0627\u062a \u0645\u0633\u0624\u0648\u0644\u0629 \u0639\u0646 \u0625\u0646\u062a\u0627\u062c \u0627\u0644\u0633\u0644\u0633\u0644\u0629 \u0627\u0644\u062b\u0642\u06cc\u0644\u0629 ( heavy chain ) \u0648 \u062c\u064a\u0646\u0627\u062a \u0645\u0633\u0624\u0648\u0644\u0629 \u0639\u0646 \u0625\u0646\u062a\u0627\u062c \u0627\u0644\u0633\u0644\u0633\u0644\u0629 \u0627\u0644\u062e\u0641\u06cc\u0641\u0629 ( light chain ) \u060c \u0648\u0647\u0630\u0647 \u0627\u0644\u062c\u064a\u0646\u0627\u062a \u0645\u0648\u062c\u0648\u062f\u0629 \u0641\u064a \u0627\u0644\u0643\u0631\u0648\u0645\u0648\u0633\u0648\u0645 \u0627\u0644\u0645\u0648\u062c\u0648\u062f \u0641\u064a DNA \u062e\u0644\u064a\u0629 \u0627\u0644\u0628\u0644\u0627\u0632\u0645\u0627. \u0627\u0644\u062c\u064a\u0646 \u0627\u0644\u0627\u0648\u0644 \u0647\u0648 VDJ ) variable (V), diversity (D) and joining (J) \u060c \u0633\u0648\u0641 \u064a\u0642\u0648\u0645 \u0647\u0630\u0627 \u0627\u0644\u062c\u064a\u0646 \u0628\u0625\u0639\u0627\u062f\u0647 \u062a\u0643\u0648\u064a\u0646 segment recombination \u0644\u0625\u0646\u062a\u0627\u062c \u0627\u0644\u0633\u0644\u0633\u0644\u0629 \u0627\u0644\u062b\u0642\u06cc\u0644\u0629\u060c \u0623\u0645\u0627 \u0627\u0644\u062c\u064a\u0646 ( VJ ) \u0641\u0647\u0648 \u0645\u0633\u0624\u0648\u0644 \u0639\u0646 \u062a\u0643\u0648\u064a\u0646 \u0627\u0644\u0633\u0644\u0633\u0644\u0629 \u0627\u0644\u062e\u0641\u06cc\u0641\u0629.<\/p>\n

     <\/p>\n

    \u0643\u0644 \u0647\u0630\u0627 \u0627\u0644\u0627\u0645\u0648\u0631 \u062a\u062d\u062f\u062b \u062a\u062d\u062a \u062a\u0623\u062b\u064a\u0631 \u0625\u0634\u0627\u0631\u0627\u062a \u0627\u0644( IL4 ) \u0627\u0644\u062a\u064a \u0633\u0648\u0641 \u062a\u0624\u062b\u0631 \u0639\u0644\u0649 ( DNA ) \u0627\u0644\u062e\u0644\u064a\u0629 \u0648 \u062a\u0643\u0648\u0646 ( mRNA ) \u0627\u0644\u0630\u064a \u0633\u0648\u0641 \u064a\u0630\u0647\u0628 \u0627\u0644\u0649 \u0627\u0644\u0631\u0627\u064a\u0628\u0648\u0633\u0631\u0645\u0627\u062a \u0627\u0644\u0645\u0648\u062c\u0648\u062f\u0629 \u0641\u064a \u0627\u0644\u0633\u0627\u064a\u062a\u0648\u0628\u0644\u0627\u0632\u0645\u060c \u0648 \u0628\u0639\u062f\u0647\u0627 \u0633\u0648\u0641 \u064a\u0646\u062a\u062c \u0627\u0644\u0631\u0627\u064a\u0628\u0648\u0633\u0648\u0645 \u0627\u0644\u0633\u0644\u0633\u0644\u062a\u064a\u0646 \u0627\u0644\u062b\u0642\u064a\u0644\u0629 \u0648 \u0627\u0644\u062e\u0641\u064a\u0641\u0629 \u0641\u064a \u062f\u0627\u062e\u0644\u0647\u060c \u062b\u0645 \u064a\u0642\u0648\u0645 \u0628\u0625\u062e\u0631\u0627\u062c \u0647\u0630\u0627 \u0627\u0644\u0633\u0644\u0627\u0633\u0644 \u0627\u0644\u0649 \u0627\u0644\u0633\u0627\u064a\u062a\u0648\u0628\u0644\u0627\u0632\u0645\u060c \u0648 \u0641\u064a \u0627\u0644\u0633\u0627\u064a\u062a\u0648\u0628\u0644\u0627\u0632\u0645 \u0633\u0648\u0641 \u062a\u062c\u0645\u0639 \u0647\u0630\u0647 \u0627\u0644\u0633\u0644\u0627\u0633\u0644 \u0644\u062a\u0643\u0648\u0646 \u0627\u0644\u0623\u062c\u0633\u0627\u0645 \u0627\u0644\u0645\u0636\u0627\u062f\u0629.<\/p>\n

     <\/p>\n

    \u0647\u0630\u0627 \u0627\u0644\u062c\u0633\u0645 \u0627\u0644\u0645\u0636\u0627\u062f \u0647\u0648 \u062e\u0627\u0635 \u0628\u0627\u0644\u0645\u0633\u062a\u0636\u062f \u0627\u0644\u0630\u064a \u062f\u062e\u0644 \u0645\u0646 \u0627\u0644\u0628\u062f\u0627\u064a\u0647 \u0644\u0644\u062c\u0633\u0645\u060c \u0648 \u0641\u064a\u0647 \u062c\u0645\u064a\u0639 \u0627\u0644\u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0644\u0647\u0630\u0627 \u0627\u0644\u0645\u0633\u062a\u0636\u062f. \u0648\u0627\u0644\u0644\u0627\u0646 \u0643\u064a\u0641 \u062a\u062a\u0645 \u0639\u0645\u0644\u064a\u0647 \u0625\u0637\u0644\u0627\u0642\u0647 \u0645\u0646 \u062e\u0644\u0627\u06cc\u0627 \u0627\u0644\u0628\u0644\u0627\u0632\u0645\u0627 \u0627\u0644\u0649 \u0627\u0644\u062c\u0633\u0645 \u061f<\/p>\n

    \u062a\u062c\u062a\u0645\u0639 \u0627\u0644\u0623\u062c\u0633\u0627\u0645 \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u062a\u062d\u062a \u063a\u0634\u0627\u0621 \u062e\u0644\u064a\u0647 \u0627\u0644\u0628\u0644\u0627\u0632\u0645\u0627 ( plasma cell ) \u060c \u062b\u0645 \u064a\u0646\u062f\u0645\u062c\u0648\u0646 \u0645\u0639 \u0627\u0644\u063a\u0634\u0627\u0621 \u0639\u0644\u0649 \u0634\u0643\u0644 \u062d\u0648\u064a\u0635\u0644\u0627\u062a \u0623\u064a \u0628\u0645\u0639\u0646\u0649 \u0623\u062f\u0642 \u062a\u0646\u062f\u0645\u062c \u0645\u0639 \u0627\u0644\u062c\u062f\u0627\u0631 \u062b\u0645 \u062a\u0639\u0645\u0644 \u0627\u0644\u062e\u0644\u064a\u0629 \u06a9\u0645\u0636\u062e\u0629 \u0644\u0644\u0623\u062c\u0633\u0627\u0645 \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u0648 \u062a\u062e\u0631\u062c \u062e\u0627\u0631\u062c \u0627\u0644\u062e\u0644\u064a\u0647 \u0648 \u062a\u0630\u0647\u0628 \u0627\u0644\u0649 \u0627\u0644\u062f\u0645 \u0623\u0648 \u0627\u0644\u0644\u0645\u0641 \u0623\u0648 \u0623\u064a \u0645\u0643\u0627\u0646 \u0641\u064a \u0627\u0644\u062c\u0633\u0645 \u060c \u0641\u062a\u0631\u0629 \u062d\u064a\u0627\u062a \u0627\u0644\u062e\u0644\u0627\u06cc\u0627 \u0627\u0644\u0628\u0644\u0627\u0632\u0645\u06cc\u0629 \u0645\u0646 ( \u0662-\u0663 ) \u064a\u0648\u0645 . \u0644\u0630\u0644\u0643 \u062a\u0648\u062c\u062f \u0627\u0644\u0645\u0644\u0627\u064a\u064a\u0646 \u0645\u0646 \u0647\u0630\u0647 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0641\u064a \u062c\u0633\u0645\u0646\u0627 \u064a\u0648\u0645\u064a\u0627 .<\/p>\n

    \u062a\u0630\u0647\u0628 \u0627\u0644\u0623\u062c\u0633\u0627\u0645 \u0627\u0644\u0645\u0636\u0627\u062f\u0629 \u0627\u0644\u0649 \u062c\u0645\u064a\u0639 \u0623\u0646\u062d\u0627\u0621 \u0627\u0644\u062c\u0633\u0645 \u0644\u0643\u064a \u062a\u062a\u0639\u0631\u0641 \u0639\u0644\u0649 \u0627\u0644\u0645\u0633\u062a\u0636\u062f \u0627\u0644\u0630\u064a \u0635\u0646\u0639\u062a \u0644\u0627\u062c\u0644\u0647\u060c \u0648\u0647\u0630\u0627 \u0628\u062f\u0648\u0631\u0647 \u0633\u0648\u0641 \u064a\u0631\u062a\u0628\u0637 \u0628\u0645\u062d\u0627\u0636\u0631\u0629 \u0623\u062e\u0631\u0649 \u0639\u0646 \u062a\u062d\u064a\u064a\u062f \u0627\u0644\u0627\u062c\u0633\u0627\u0645 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0644\u0645\u0633\u062a\u0636\u062f\u0627\u062a \u0627\u0644\u0644\u0642\u0627\u062d \u060c \u0633\u0648\u0641 \u0623\u0643\u062a\u0628\u0647\u0627 \u0641\u064a \u0648\u0642\u062a \u0642\u0631\u064a\u0628 .<\/p>\n

    \u0627\u0644\u0634\u0643\u0631 \u0627\u0644\u062c\u0632\u064a\u0644 \u0625\u0644\u0649 \u0623\u0633\u0627\u062a\u0630\u062a\u064a ( \u0627\u0644\u062f\u0643\u062a\u0648\u0631 \u0639\u0628\u062f \u0627\u0644\u062c\u0628\u0627\u0631 \u0627\u0644\u0634\u0645\u0631\u064a \u0648\u0627\u0644\u062f\u0643\u062a\u0648\u0631 \u0639\u0628\u062f \u0627\u0644\u0644\u0647 \u0634\u0627\u0647\u064a\u0646 ).<\/p>","protected":false},"excerpt":{"rendered":"

    How Antibodies Are Made and How They Destroy Antibodies Dr. […]<\/p>","protected":false},"author":1,"featured_media":4736,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,75],"tags":[],"class_list":["post-4735","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-articles","category-news"],"_links":{"self":[{"href":"https:\/\/nahrainveterinary.com\/ar\/wp-json\/wp\/v2\/posts\/4735","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nahrainveterinary.com\/ar\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nahrainveterinary.com\/ar\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nahrainveterinary.com\/ar\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nahrainveterinary.com\/ar\/wp-json\/wp\/v2\/comments?post=4735"}],"version-history":[{"count":0,"href":"https:\/\/nahrainveterinary.com\/ar\/wp-json\/wp\/v2\/posts\/4735\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nahrainveterinary.com\/ar\/wp-json\/wp\/v2\/media\/4736"}],"wp:attachment":[{"href":"https:\/\/nahrainveterinary.com\/ar\/wp-json\/wp\/v2\/media?parent=4735"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nahrainveterinary.com\/ar\/wp-json\/wp\/v2\/categories?post=4735"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nahrainveterinary.com\/ar\/wp-json\/wp\/v2\/tags?post=4735"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}